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KMID : 0377619760300060677
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Korean Jungang Medical Journal
1976 Volume.30 No. 6 p.677 ~ p.683
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Bacterial Relapse in Leprosy Patients Receiving Treatment
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徐治均/Suh, Chee Kyun
金在福/鄭祥立/Jun, Jae Bok/Chung, Sang Lip
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Abstract
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The purpose of this study is to discuss .various aspects of bacterial relapse in leprosy patients receiving treatment. Between 1957-1975 a total of 2910 leprosy patients were registered at The Leprosy Mission Hospital in Daegu. The authors, have analyzed the treatment of these patients and the results are as follows:
1. Of the total number of patients registered 26.9%(783 cases) were positive le
lepromatous patients. Among these promatous patients ls6 case consorted to bacteriologically negative after therapy.
2. Of the 186 converted cases, 66% had converted after five years while an. 83 %o conversion rate was reported after 6 years.
3. Among, the total number of patients analyzed, bacterial relapse was reported
in 31 cases, 23 of these being promatous patients.
4. After converting from positive to negative, 17. of.~-the above´ mentioned 23 promatous cases reconverted back to positive(9.1%). Most re conversions of this nature were found to occur within the first three years after becoming negative.
5. The most common symptoms of the relapse cases were neuritis and neural gia, while cutaneous manifestations were also reported.
6. T he most of bacterial relapse. cases the bacterial indeces ranged from 1. 0 to 2.9 while the morphologic indeces usually remained below 10.
7. The two most frequent causes of bacterial relapse were irregular treatment or too low a drug-regiment (16 cases). Release from control and resistance to DDS were also significant.
8. The majority of patients with bacterial relapse after release from control who had received regular treatment for 5 additional years after apparent cessation of disease activity, was of lepromatous type and relapse occurred most frequently within the first 3 years.
9 Fourteen out of the original 31 relapse patients returned to negative while 17 remained positive during receiving treatment for 5 months to 5 years.
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